significantly changed between before and after VAE treatment in both test and control group. The concentration of IL-6 in the test group was increased from 8.19 ±1.75 pg/mL to 9.86±1.46 pg/mL after treatment (p=0.013). The concentration of IFN-g in the test group was remarkably increased from 91.76±17.16 pg/mL to 167.42±66.61 pg/mL after treatment (p=0.009). Conclusion: Significant increases in the concentration of IL-6 and IFN-g were observed after VAE treatment. These results suggest that VAE treatment can stimulate immune responses, especially cell-mediated immunity in immune-compromised patients received the chemoradiation for breast cancer.
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Son et al. (2010) studied this question.
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