Target Factor Modeling of Migration Behavior in Capillary Electrophoresis

This paper describes a target factor analysis based technique to model migration behavior in capillary electrophoresis (CE). The technique is effective in reducing the initial number of experiments required for modeling, as well as in recognizing the optimum conditions for running these experiments. The technique can be applied to optimize any number of parameters. The usefulness of the technique is demonstrated via both the experimentally obtained and the simulated data sets. Examples are provided to describe optimization of one and two parameters.