Lipoprotein(a), smoking, and diabetes are additive but not interactive risk factors for major adverse cardiovascular events after acute coronary syndrome

Gregory G. Schwartz; Michael Szarek; Vera Bittner; Deepak L. Bhatt; Rafael Dı́az; Shaun G. Goodman; Robert A. Harrington; Ghada Hassan; J. Wouter Jukema; Irena Stevanovic; Hagai Tavori; Samantha Thielen; Harvey D. White; Philippe Gabríel Steg

doi:10.1016/j.ajpc.2026.101747

August 1, 2026American Journal of Preventive CardiologyOpen Access

Lipoprotein(a), smoking, and diabetes are additive but not interactive risk factors for major adverse cardiovascular events after acute coronary syndrome

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Key result

Lp(a), smoking, and diabetes confer additive without interactive risks for MACE after ACS.

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Implication

Supports additive risk stratification incorporating Lp(a), smoking, and diabetes post-ACS; leaves open interaction effects in larger prospective cohorts.

Abstract

cardiovascular events after acute coronary syndrome

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Schwartz et al. (2026) studied this question. Lipoprotein(a), smoking, and diabetes are additive but not interactive risk factors for major adverse cardiovascular events after acute coronary syndrome.

synapsesocial.com/papers/6a9a8b29fb1a12d5ce3470e3 https://doi.org/10.1016/j.ajpc.2026.101747

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Lipoprotein(a), smoking, and diabetes are additive but not interactive risk factors for major adverse cardiovascular events after acute coronary syndrome

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Implication

Abstract

Discussion

Cite This Study

Lipoprotein(a), smoking, and diabetes are additive but not interactive risk factors for major adverse cardiovascular events after acute coronary syndrome

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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