Key result
This review summarizes the influence and possible mechanisms of growth hormone treatment on the pathogenesis and progression of scoliosis to guide future research.
Why the study?
The safety of growth hormone treatment remains debatable, particularly regarding its effect on the occurrence and progression of scoliosis.
Does growth hormone therapy affect the occurrence or progression of scoliosis in patients with growth retardation?
Does growth hormone therapy affect the occurrence or progression of scoliosis in patients with growth retardation?
This review summarizes the potential effects and mechanisms of growth hormone therapy on the pathogenesis and progression of scoliosis.
Answers are grounded in this paper and cite their sources.
Growth hormone may influence scoliosis progression in growth-retarded youth; leaves open need for prospective trials before practice change.
Growth hormone (GH) therapy has been used in patients with growth retardation and short stature due to various reasons. The safety of GH treatment is still debatable, one of which is the occurrence and development of scoliosis. In order to explore the effects of GH on the occurrence or progression of scoliosis, this review summarizes previous studies, summarizes the influence of GH treatment on the pathogenesis and progression of scoliosis, and analyzes the possible mechanism of GH in the pathogenesis and progression of scoliosis. Hopefully, it can provide a direction for future research.
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Zhang et al. (2023) conducted a review in Growth retardation and short stature. Growth hormone (GH) therapy was evaluated on Occurrence and development of scoliosis. This review summarizes the influence and possible mechanisms of growth hormone treatment on the pathogenesis and progression of scoliosis to guide future research.
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