Key result
Foot-and-mouth disease virus was released from the mammary gland secretory epithelium of infected cows via an exocytotic mechanism, with lytic release observed in 20% of preparations.
Population
Uninfected cows exposed to pigs with foot-and-mouth disease
Design
Preclinical
Authors
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Hypothesis-generating for FMDV shedding in dairy cattle; extends mechanistic models but requires in vivo validation before practice implications.
Foot-and-mouth disease virus is released from bovine mammary gland secretory cells via an exocytotic mechanism similar to milk-fat globule release.
Blackwell et al. (1981) studied Foot-and-mouth disease. Contact exposure to foot-and-mouth disease was evaluated on Mechanism of virus release from mammary gland secretory epithelium. Foot-and-mouth disease virus was released from the mammary gland secretory epithelium of infected cows via an exocytotic mechanism, with lytic release observed in 20% of preparations.
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