An in vivo method for the study of mucociliary activity in the human trachea and bronchi is presented. The method is based on a two-way fibre-optic system whereby reflections of light emitted by one glass-fibre and reflected by the cilia are picked up by a second glass fibre and transmitted to a recording unit. The glass fibre system is designed to be used in conjunction with a regular fibre bronchoscope, and is convenient for routine use in daily clinical work. As reference material, 15 subjects aged 23-73 years without evidence of disease were examined in their right upper bronchus. The average cilial beat frequency was found to be 12.0 +/- 1.0 (SD) waves per second.
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D. Huberman (1993) studied this question.
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