Key result
Hypertension with morning surge increased the risk of left ventricular hypertrophy on electrocardiogram by 3.17 times compared with hypertension without morning surge (p < 0.05).
Why the study?
Data assessing electrocardiographic left ventricular hypertrophy and 24-hour ambulatory blood pressure parameters were limited in hypertensive patients in Vietnam.
Do 24-hour ambulatory blood pressure parameters predict left ventricular hypertrophy on electrocardiogram in hypertensive patients?
Cross-Sectional (n=101)
No
Do 24-hour ambulatory blood pressure parameters predict left ventricular hypertrophy on electrocardiogram in hypertensive patients?
Morning blood pressure surge and 24-hour ambulatory blood pressure parameters are significantly associated with an increased risk of electrocardiographic left ventricular hypertrophy in hypertensive patients.
Answers are grounded in this paper and cite their sources.
Morning surge may mark higher ECG-LVH risk in hypertension; hypothesis-generating for ABPM parameters and needs prospective validation.
Background: Left ventricular hypertrophy in hypertensive patients is an early complication, related to blood pressure control and the appearance of arrhythmias, especially atrial fibrillation, once it appears, the patient has been stratified to a high cardiovascular risk. 24 - hour ambulatory blood pressure predicted cardiovascular risk and target organ damage stronger than office blood pressure. However, in Vietnam, there are not many assessment of left ventricular hypertrophy detected on electrocardiogram. Therefore, we conducted our study, studying left ventricular hypertrophy on electrocardiogram and some parameters of 24-hour ambulatory blood pressure in hypertensive patients.Methods: 101 patients admitted to the Department of Cardiology, Hue Central Hospital, diagnosed with hypertension according to the Vietnam Society of Hypertension 2022 and previously treated for hypertension. Electrocardiogram and 24-hour ambulatory blood pressure monitoring were performed. The study method was a cross-sectional descriptive study with comparison.Results: In the hypertensive group with/without left ventricular hypertrophy on electrocardiogram, the rate of morning surge was 73.33% vs. 46.48% (p < 0.05). Hypertension with morning surge increased the risk of left ventricular hypertrophy on electrocardiogram by 3.17 times compared with hypertension without morning surge (p < 0.05) and increased the risk of increased Sokolow - Lyon voltage index on electrocardiogram by 9.03 times (p < 0.05). There was a weak positive correlation between 24-hour mean SBP and day mean SBP with the Cornell index and the GubnerUngerleider index with p < 0.05. There was a weak positive correlation between the Cornell index and the GubnerUngerleider index with p < 0.05. There was a weak positive correlation between the night-time mean SBP and nighttime mean DBP with the Cornell index with p < 0.05.Conclusion: 24 - hour ambulatory blood pressure parameters predict the appearance of left ventricular hypertrophy detected on electrocardiogram, as well as provide information to treat hypertension.
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Pham Quang Tuan (2024) conducted a cross-sectional in Hypertension (n=101). Morning surge in blood pressure vs. No morning surge was evaluated on Left ventricular hypertrophy on electrocardiogram (RR 3.17, p=<0.05). Hypertension with morning surge increased the risk of left ventricular hypertrophy on electrocardiogram by 3.17 times compared with hypertension without morning surge (p < 0.05).
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