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October 1, 2003Journal of Medical GeneticsOpen Access

Genotype-phenotype analysis of the Crohn’s disease susceptibility haplotype on chromosome 5q31

Alessandro Armuzzi

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Abstract

Background and aims: Recent molecular data suggest that genetic factors may underlie the disease heterogeneity observed in both ulcerative colitis (UC) and Crohn’s disease (CD). A locus on chromosome 5q has been implicated in susceptibility to CD, and recently refined by linkage disequilibrium mapping to a conserved 250 kb haplotype (5q31). No data regarding the …

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synapsesocial.com/papers/6a9ab6971d4856e15be913f8 https://doi.org/10.1136/jmg.40.10.792

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