Why the study?
Left ventricular rupture is a rare but lethal complication of surgical mitral valve replacement, prompting a comparison of mortality rates between two surgical techniques for correcting atrioventricular disjunction.
Does a bovine pericardium patch technique reduce mortality compared to fixing the mitral annulus with bovine pericardial strips in patients with atrioventricular disjunction after mitral valve replacement?
Population
10 patients with atrioventricular disjunction among 720 undergoing mitral valve replacement
Comparison
Bovine pericardium patch covering the posterior LV wall vs mitral annulus fixation with bovine pericardial strips
Design
Single-center retrospective cohort study
Key result
Correction of atrioventricular disjunction using a bovine pericardium patch resulted in lower mortality (25%) compared to fixing the mitral annulus with pericardial strips (100%).
Authors
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Patch technique may warrant study but should not yet change practice; leaves open need for randomized confirmation in atrioventricular disjunction.
Cohort (n=10)
No
Does a bovine pericardium patch technique reduce mortality compared to fixing the mitral annulus with bovine pericardial strips in patients with atrioventricular disjunction after mitral valve replacement?
Absolute Event Rate: 25% vs 100%
A bovine pericardium patch technique covering the posterior wall of the left ventricle appears to significantly reduce mortality compared to simple annulus fixation with pericardial strips in patients experiencing atrioventricular disjunction after mitral valve replacement.
Sobral et al. (2019) conducted a cohort in Atrioventricular disjunction after mitral valve replacement (n=10). Bovine pericardium patch sutured from papillary muscle base to posterior wall of left atrium (Group II technique) vs. Mitral annulus fixed with bovine pericardial strips (Group I technique) was evaluated on Mortality rate. Correction of atrioventricular disjunction using a bovine pericardium patch resulted in lower mortality (25%) compared to fixing the mitral annulus with pericardial strips (100%).