Key result
Correction of atrioventricular disjunction using a bovine pericardium patch resulted in lower mortality (25%) compared to fixing the mitral annulus with pericardial strips (100%).
Why the study?
Left ventricular rupture is a rare but lethal complication of surgical mitral valve replacement, prompting a comparison of mortality rates between two surgical techniques for correcting atrioventricular disjunction.
Does a bovine pericardium patch technique reduce mortality compared to fixing the mitral annulus with bovine pericardial strips in patients with atrioventricular disjunction after mitral valve replacement?
Cohort (n=10)
No
Does a bovine pericardium patch technique reduce mortality compared to fixing the mitral annulus with bovine pericardial strips in patients with atrioventricular disjunction after mitral valve replacement?
A bovine pericardium patch technique covering the posterior wall of the left ventricle appears to significantly reduce mortality compared to simple annulus fixation with pericardial strips in patients experiencing atrioventricular disjunction after mitral valve replacement.
Answers are grounded in this paper and cite their sources.
Patch technique may warrant study but should not yet change practice; leaves open need for randomized confirmation in atrioventricular disjunction.
Objective: A left ventricular rupture is a rare but lethal complication of surgical mitral valve replacement. We compared the mortality rates of two different surgical techniques for the correction of atrioventricular disjunction. Methods: From January 2005 to January 2012, 720 patients underwent mitral valve replacement at our institution. Two different surgical techniques were used for the correction of atrioventricular disjunction. The techniques were: in group I, the mitral annulus was fixed with bovine pericardial strips; in group II, a 'patch' of bovine pericardium was sutured; the patch extended from the base of the lateral and medial papillary muscle, covered the posterior wall of the left ventricle, went through the posterior mitral annulus, and ended in the posterior wall of the left atrium adjacent to the mitral ring. Results: Atrioventricular disjunction occurred in 10 (1.39%) of 720 patients, out of which the group I technique was used in 6 (60%) patients, and the group II technique in 4 (40%) patients. The mortality rate for the group I technique was 100% (6 patients) with 5 deaths in the operating room and 1 death from postoperative cardiogenic shock. For the group II technique, the mortality rate was 25% (1 patient) and the death was associated with late pulmonary sepsis. Conclusion: The group II technique showed a lower mortality, and was more efficient than the group I technique.
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Sobral et al. (2019) conducted a cohort in Atrioventricular disjunction after mitral valve replacement (n=10). Bovine pericardium patch sutured from papillary muscle base to posterior wall of left atrium (Group II technique) vs. Mitral annulus fixed with bovine pericardial strips (Group I technique) was evaluated on Mortality rate. Correction of atrioventricular disjunction using a bovine pericardium patch resulted in lower mortality (25%) compared to fixing the mitral annulus with pericardial strips (100%).
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