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An ESIPT based fluorescent sensor 1 was developed, which could selectively detect and differentiate trivalent metal ions Cr(3+), Al(3+) and Fe(3+) in aqueous medium. The cell imaging experiments confirmed that 1 can be used for monitoring intracellular Cr(3+) and Al(3+) levels in living cells.
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Wang et al. (2014) studied this question.
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