Bacterial outer membrane vesicle biogenesis: a new mechanism and its implications

Bacterial outer membrane vesicle biogenesis: a new mechanism and its implications – Current OMV biogenesis models are based on either loss or relocation of covalent linkages between the OM and the underlying peptidoglycan layer, require an accumulation of peptidoglycan fragments or misfolded proteins in the periplasmic space, or need the enrichment of species-specific membrane curvature-inducing molecules. However, these models are limited by the fact that they either (...)