A patient with previously diagnosed chronic lymphocytic leukemia developed progressive multifocal leukoencephalopathy (PML) and was treated with cytarabine, with a clinical remission. Histologic studies of a brain biopsy confirmed the diagnosis of PML. Viral and immunological studies suggest that the biopsy contained a papovavirus similar to an agent isolated from another patient with PML. Further controlled clinical trials with antiviral agents are indicated.
No takes yet. Share an insight, caveat, or question.
William R. Bauer (1973) studied this question.