A previous study indicated that the sequential hourly and daily changes in plasma -globin DNA concentrations after trauma were different between mildly and severely injured patients and between patients with and without organ failure (19 ). The differences may also be useful for monitoring the progress of post-trauma complications Further studies will be required to investigate the dynamic changes in plasma mtDNA and may provide additional and valuable information on trauma prognosis. In addition, quantitative plasma mtDNA analysis may also be useful in the prognosis and monitoring of other diseases, such as cancer, and the high concentration of mtDNA in plasma may allow its use for noninvasive study of mtDNA-related diseases.
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Baldas et al. (2004) studied this question.
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