Key result
A 53-year-old man with metastatic urothelial carcinoma developed symptomatic cardiac tamponade with positive cytodiagnosis of pericardial effusion despite systemic chemotherapy.
Case Report (n=1)
Highlights a rare presentation of symptomatic cardiac metastasis from urothelial carcinoma manifesting as cardiac tamponade.
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Cardiac tamponade may signal rare urothelial carcinoma metastasis; case report leaves optimal surveillance and intervention open.
A 53-year-old man presented for further evaluation due to microscopic hematuria and left lumbar pain. Computed tomography revealed a large tumour in the left renal pelvis with multiple metastases. Despite effective systemic chemotherapy, he developed dyspnea, and was diagnosed with cardiac tamponade. Pericardial involvement in an advanced malignancy is common, but symptomatic cardiac metastasis from urothelial carcinoma is rare. Of the reports of symptomatic cardiac metastasis from urothelial carcinoma, only 3 cases presented as cardiac tamponade. We report here a rare case of cardiac tamponade caused by a renal pelvic carcinoma with positive cytodiagnosis of pericardial effusion. We also summarize and discuss the symptoms, treatment, and prognosis of the pathological condition, and present a brief review of previously published reports.
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Hattori et al. (2012) conducted a case report in Metastatic urothelial carcinoma with cardiac tamponade (n=1). Systemic chemotherapy was evaluated on Cardiac tamponade. A 53-year-old man with metastatic urothelial carcinoma developed symptomatic cardiac tamponade with positive cytodiagnosis of pericardial effusion despite systemic chemotherapy.
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