4-Aryl- NH -1,2,3-triazoles are valuable compounds in organic chemistry and pharmaceutical chemistry. In this paper, we describe a novel multicomponent reaction of aldehydes, nitroalkanes, and sodium azide for the synthesis of 4-aryl- NH -1,2,3-triazoles. In this transformation, it was found that both the slow addition of nitroalkane and the presence of NaHSO 3 /Na 2 SO 3 are advantageous to promote the reaction results. Additionally, a series of aldehydes and nitro compounds were investigated.
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Lin et al. (2015) studied this question.