Anticancer vaccine: Antigen 2 made out of a tripeptide of β-D-Galp-(1→3)-CH2-α-D-GalNAc-O-Ser and conjugated with keyhole limpet hemocyanin (KLH) protein induced an early and strong immune response (IgG antibodies) in mice. Antigen 3 made out of an α-C-galactoside analogue did not induce such an immune response (see scheme).
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Awad et al. (2012) studied this question.
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