Research Progress of Resveratrol in the Prevention and Treatment of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in clinic. Although there are various treatment methods, the overall curative effect is not effective. Resveratrol is an antitoxin secreted by plants when stimulated. It is a nonflavonoid polyphenol organic compound, which has many biological functions, such as antiplatelet aggregation, regulating lipid metabolism, anti-inflammatory, and antioxidant and so on. In recent 20 years, resveratrol has been found to have preventive and therapeutic effects on a variety of cancers. This paper reviews the prevention and treatment of hepatocellular carcinoma by resveratrol from the aspects of tumor prevention, tumor microenvironment, tumor metabolism, invasion and metastasis.