A Direct Amine‐Palladium Acetate Cocatalyzed Saegusa Oxidation Reaction of Unmodified Aldehydes to α,β‐Unsaturated Aldehydes

Abstract magnified image A direct preparation of synthetically useful α,β‐unsaturated aldehydes from readily available aldehydes has been developed. The process is effectively cocatalyzed by an amine‐palladium acetate to give rise to α,β‐unsaturated aldehydes in moderate to good yields (41–62%). The reaction features the use of unmodified aldehydes rather than enol silyl ethers, which are used in a typical Saegusa oxidation reaction.