Disc oedema in congenital amaurosis of Leber.

Background: BT is a novel treatment for severe asthma based on radiofrequent energy delivery to the airways. Although BT application is rapidly increasing worldwide, systematic radiological assessment immediately after BT has not been reported. Methods: Prospective, observational study of radiological abnormalities after BT. Chest X-rays taken <5 hours after 11 BT procedures in 5 severe asthma patients, were compared with baseline chest x-rays. In case of abnormalities, a follow-up chest x-ray and in 2 cases a chest CT was performed. Results: All 11 chest X-rays showed radiology abnormalities; subtotal lobar atelectasis (n=1), peribronchial opacities (n=4), peribronchial opacities and segmental atelectasis (n=5), peribronchial opacities, subtotal and segmental atelectasis (n=1). In 2 patients chest CT was performed <24 hours after BT; 1 patient showed subtotal lobar atelectasis, 1 patient showed bronchial wall thickening and peri-bronchial ground glass opacities. In non-BT-treated lung areas no abnormalities were detected. Most abnormalities resolved after 1 week, all completely resolved after 1-6 weeks upon standard treatment including steroids. No bronchoscopic intervention was necessary. Conclusions: BT frequently causes immediate, but transient radiology abnormalities. : Subtotal atelectasis of the right upper lobe, lingular peribronchial opacities and partial atelectasis of the anterior segments of the left upper lobe after BT of both upper lobes.