The distribution of the enzyme 5′‐nucleotidase in the brain of the mouse is described in detail. The structures showing the greatest amount of activity are the corpus striatum, the substantia gelatinosa, the lateral longitudinal stria, the nodulus of the cerebellum and parts of the retina. In the cerebellum in particular, and to some extent in the hippocampus, the distribution is such as to suggest that the enzyme may be actively involved not only in simple biochemical processes but possibly also in some neurophysiological function.
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T. G. Scott (1967) studied this question.
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