Key result
A 58-year-old woman with a history of endometrial cancer and venous thromboembolism developed catastrophic antiphospholipid syndrome in the setting of mitral valve repair.
Case Report (n=1)
This case report describes the occurrence of catastrophic antiphospholipid syndrome in the setting of mitral valve repair.
May signal catastrophic antiphospholipid syndrome risk after mitral valve repair; hypothesis-generating and leaves open need for screening or prophylaxis trials.
A 58-year-old woman was admitted to the hospital after presenting with aphasia and left middle cerebral artery stroke. The patient had a history of stage III endometrial cancer status-post chemotherapy and brachytherapy as well as deep vein thrombosis and pulmonary embolism diagnosed ∼15 months before presentation and managed with therapeutic enoxaparin. At that time, she underwent testing for antiphospholipid syndrome (APS) by lupus anticoagulant, which was negative.
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El‐Dalati et al. (2021) conducted a case report in Catastrophic antiphospholipid syndrome (n=1). Mitral valve repair was evaluated. A 58-year-old woman with a history of endometrial cancer and venous thromboembolism developed catastrophic antiphospholipid syndrome in the setting of mitral valve repair.
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