The long-sought-after palladium-catalyzed coupling of silyl enol ethers, both cyclic and acyclic, with a wide range of aryl bromides and chlorides to form α-aryl ketones is realized. The key to effective activation of the silicon enolate was the use of two metal fluoride additives, which operate in a synergistic fashion.
No takes yet. Share an insight, caveat, or question.
Su et al. (2006) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: