Key result
Complete removal of the pacemaker device was required to cure a recurrent bloodstream infection caused by Staphylococcus aureus small colony variants that was unresponsive to prolonged antimicrobial therapy.
Case Report (n=1)
No
This first reported case of a pacemaker-related bloodstream infection caused by S. aureus small colony variants highlights the necessity of complete device removal for cure due to poor response to antimicrobial therapy.
May require complete device removal for refractory S. aureus SCV pacemaker infections; leaves generalizability open as first case report.
We describe the first known case of a device-related bloodstream infection caused by Staphylococcus aureus small colony variants. Recurrent pacemaker-related bloodstream infection within a 7-month period illustrates the poor clinical and microbiologic response to prolonged antimicrobial therapy in a patient infected with this S. aureus subpopulation.
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Seifert et al. (2003) conducted a case report in Pacemaker-related bloodstream infection (n=1). Antimicrobial therapy and complete device removal was evaluated on Clinical cure. Complete removal of the pacemaker device was required to cure a recurrent bloodstream infection caused by Staphylococcus aureus small colony variants that was unresponsive to prolonged antimicrobial therapy.
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