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There is an urgent need for immunomodulatory treatments for patients with atopic eczema (AE) (i.e., atopic dermatitis), in particular for those with disease recalcitrant to topical therapies. The only conventional systemic therapy approved by the European Medicines Agency is cyclosporine, and that is approved only for adults. In the United States, only oral corticosteroids and dupilumab have Food and Drug Administration approval.
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Spuls et al. (2017) studied this question.
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