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The biogenic acids 1-trans-2,3-epoxysuccinic acid and succinic acid accumulate in decationized refiner's blackstrap molasses shake cultures of Paecilomyces varioti Bainier. The maximum accumulation of 1-trans-2,3-epoxysuccinic acid occurred in a medium which contained Cu2+ and Fe3+ at concentrations of 1.0 and 2.0 mM, respectively. The maximum accumulation of succinic acid occurred in a culture medium which contained Cu2+ at a concentration of 0.01 mM and Fe3+ at a concentration of 1.0 mM.
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Ling et al. (1978) studied this question.
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