Key result
A second-order extension of the Rush-Larsen scheme outperformed the original method for all test cases and was more efficient than a second-order Runge-Kutta solver for stiff problems.
Population
Dynamic models of cardiac cell electrophysiology
Comparison
Second-order algorithm extending the Rush-Larsen… vs Original Rush-Larsen method and a second-order…
Authors
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May accelerate stiff cardiac cell simulations; leaves open validation and clinical translation of models.
A novel second-order numerical scheme improves accuracy and efficiency over traditional methods for modeling cardiac cell electrophysiology, particularly in stiff problems.
Sundnes et al. (2009) studied dynamic models of cardiac cell electrophysiology. Second-order extension of the Rush-Larsen scheme vs. Original Rush-Larsen method and a second-order Runge-Kutta (RK) method was evaluated on Error and computational load. A second-order extension of the Rush-Larsen scheme outperformed the original method for all test cases and was more efficient than a second-order Runge-Kutta solver for stiff problems.
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