Key result
Elderly patients undergoing combined AVR and CABG had significantly lower 60-month freedom from cardiac-related death compared to younger patients (85% vs 94%; p=0.023).
Why the study?
Does older age worsen clinical outcomes and intraoperative management in patients undergoing simultaneous aortic valve replacement and coronary artery bypass grafting?
Cohort (n=452)
Does older age worsen clinical outcomes and intraoperative management in patients undergoing simultaneous aortic valve replacement and coronary artery bypass grafting?
Absolute Event Rate: 85% vs 94%
p-value: p=0.023
Elderly patients undergoing combined AVR and CABG have more extensive coronary artery disease, receive less complete revascularization, and experience higher early morbidity and lower long-term survival compared to younger patients.
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Reduced cardiac survival in elderly after AVR+CABG; leaves open whether age-specific strategies improve outcomes.
Perek et al. (2018) conducted a cohort in Aortic stenosis and coronary artery disease (n=452). Elderly age (>71 years) vs. Young age (<58 years) was evaluated on 60-month freedom from cardiac-related death (p=0.023). Elderly patients undergoing combined AVR and CABG had significantly lower 60-month freedom from cardiac-related death compared to younger patients (85% vs 94%; p=0.023).
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