Goiter and Myxedema Following Prolonged Ingestion of Iodine: Report of a Case With Evidence of Unusual Thyroid Dysfunction

Attention has been directed recently to the occasional role of intrinsic defects in the thyroid mechanism for the conversion of inorganic iodide to thyroid hormone as a cause of goiter and hypothyroidism (1–9). The possible role of chronic or excessive iodine administration in the production of goiter and hypothyroidism has also been emphasized in several clinical reports (10–14). The case here described presents features compatible with both these causes of thyroid dysfunction and enlargement.