Naturally occurring! The cyanobacterial metabolite 7-deoxycylindrospermopsin has been synthesized and its natural occurrence confirmed by HPLC. Structural analysis and protein-inhibition studies show that the uracil unit does not appear to adopt the unconventional tautomeric structure (see scheme), as previously thought, and that oxygenation at C7 is not required for the inhibition of protein biosynthesis.
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Looper et al. (2005) studied this question.
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