Integrated regional genetic services: current and future provisionCommentary: The future development of regional genetic services will rely on partnerships

# Integrated regional genetic services: current and future provision {#article-title-2} This is an important time in the history of genetics. Now that we have the sequence of the human genome in “working draft” form commentators predict a huge increase in activity in genetic medicine. Here we describe how the benefits of this rapidly expanding knowledge are being brought to the UK population as genetic services, and how they may develop in the future. Few doubt that medicine will be increasingly founded on the understanding of genetics and underpinned by testing. The biggest uncertainty concerns the large scale genetic screening of healthy people for susceptibility to common diseases: how widely this will happen, how soon, and how it might be organised. #### Summary points UK genetic services are based on a network of geographical centres offering specialist services to families at high risk of serious genetic disorders Regional genetic centres provide diagnosis, risk estimation, counselling, surveillance, and support Links with secondary and tertiary specialists are established, and links with primary care are being developed Genetic counsellors have a key role in the delivery of integrated services Genetic testing is already helping many families at high risk and in the future will play a central part in the clinical management and prescribing practice for all specialties The role of testing for genetic variants predisposing to common diseases has yet to be established Our information derives from the experience of the regional genetic centres in 12 UK health regions and international comparisons reported in recent scientific and official publications. Our vision for the development of integrated genetic services draws on these sources, recent initiatives to commission genetic services, and the literature on the impact of the new genetics in medicine. #### Genetic centres Special skills Correspondence to: D Ravine