A composite of collagen (COL) and hydroxyapatite(HA) was prepared using a biomimetic approach, which performs a direct nucleation of HA on self‐ assembled collagen matrix. This research may be helpful to understand the possible mechanisms for collagen‐mediated mineralization in general and the COL/HCA composite can be considered a new particularly attractive material for human bone tissue implantation.
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Wang et al. (2006) studied this question.
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