Key result
A collapsible tube model simulating mitral valve closure demonstrated that the flexible tube first closes near its upstream end, followed by a propagation process toward the downstream end.
This experimental and theoretical fluid mechanics model demonstrates that mitral valve closure initiates at the upstream end and propagates downstream.
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Model suggests upstream-initiated mitral closure propagation; hypothesis-generating and should not yet inform clinical practice.
The fluid mechanics of the closure motion of a short collapsible tube segment, subject to a strong flow deceleration as in one of Henderson & Johnson's (1912) experiments, is investigated experimentally and theoretically. Physical similarity to the closure process of the mitral valve is obtained. In the study particular emphasis is placed upon the evolution of the longitudinal profiles of the collapsible tube during its closure motion. It is found that the flexible tube first closes near its upstream end and that this first phase is followed by a propagation process toward the downstream end. The characteristics of this typical sequence and of the longitudinal shape of the collapsible tube are related to hydrodynamic parameters. The results predicted by the theory agree consistently with those obtained from the experiments.
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Bitbol et al. (1982) studied Mitral valve closure dynamics. Collapsible tube model was evaluated on Evolution of the longitudinal profiles of the collapsible tube during its closure motion. A collapsible tube model simulating mitral valve closure demonstrated that the flexible tube first closes near its upstream end, followed by a propagation process toward the downstream end.
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