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September 5, 2026BioMedInformaticsOpen Access

Deep Learning-Based Malaria Classification Using Single- and Dual-Branch CNN Architectures with Attention Modules

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Authors

SMSimona MoldovanuGTGigi TăbăcaruDMDan Munteanu

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Overview

Computational study demonstrates improved malaria parasite classification using attention-enhanced convolutional networks, highlighting the diagnostic power of dual-branch architectures.

Key Points

  • To identify and evaluate optimal single- and dual-branch convolutional neural network architectures enhanced with attention mechanisms for accurate malaria parasite classification.
  • Evaluated single-branch (SB-CNN) and dual-branch (DB-CNN) architectures using EfficientNet-B0 and EfficientNet-B3 as backbone networks.
  • Integrated Convolutional Block Attention Modules (CBAM), Efficient Channel Attention (ECA), and Squeeze-and-Excitation (SE) blocks to enhance feature representation.
  • Evaluated model variants using 5-fold cross-validation on the Thick blood smear dataset and visualized high-dimensional feature distributions with t-SNE.
  • Single-branch EfficientNet-B3 both alone and combined with CBAM ranked among the top-performing classification models on the Thick dataset.
  • Dual-branch EfficientNet-B3 incorporating CBAM in the primary branch and SE in the secondary branch also demonstrated top-tier classification performance.

Cite This Study

Moldovanu et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd4536b95aff0620ebebehttps://doi.org/10.3390/biomedinformatics6050067
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