What does this research mean for the field?

Less favorable medication attitudes and polypharmacy are independently associated with noncomplete medication adherence in adolescents receiving psychopharmacological treatment across various psychiatric disorders. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To assess medication attitudes across a diverse psychiatric adolescent population and identify clinical and demographic factors linked to noncomplete adherence.

September 5, 2026Journal of Child and Adolescent Psychopharmacology

Factors Influencing Medication Adherence in Adolescents with Psychiatric Disorders: Quantitative Results from a Multicenter Mixed-Methods Study

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Authors

FHFlorian Handermann CBClara Both LNLarissa Niemeyer

Discussion

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Overview

Multicenter study reveals that negative treatment attitudes and polypharmacy decrease medication adherence in adolescents with psychiatric disorders, highlighting key targets for clinical support.

Key Points

To assess medication attitudes across a diverse psychiatric adolescent population and identify clinical and demographic factors linked to noncomplete adherence.
Conducted a secondary analysis of the multicenter SEMA study comprising N = 75 adolescents aged 12–17 years receiving psychopharmacological therapy.
Assessed treatment attitudes via the Questionnaire on Attitudes Toward Treatment (QATT) and adherence via the Medication Adherence Report Scale (MARS), classifying adherence as complete or noncomplete.
Performed group comparisons alongside multivariable logistic regression to identify independent factors predicting noncomplete medication adherence.
A total of 40% of adolescents were classified as not completely adherent to their medication regimen.
Higher QATT scores, reflecting less favorable medication attitudes, were observed among older adolescents, inpatients, individuals with internalizing disorders, and those with noncomplete adherence.
In multivariable logistic regression, higher QATT scores (OR = 1.05, 95% CI: 1.00–1.10; p = 0.048) and polypharmacy (OR = 3.64, 95% CI: 1.03–12.88; p = 0.046) independently predicted noncomplete medication adherence.

Cite This Study

Handermann et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd4606b95aff0620ec117 https://doi.org/10.1177/10445463261485772

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September 5, 2026Journal of Child and Adolescent Psychopharmacology

Factors Influencing Medication Adherence in Adolescents with Psychiatric Disorders: Quantitative Results from a Multicenter Mixed-Methods Study

View Full Paper

Ask AI

Bookmark

Authors

FHFlorian Handermann CBClara Both LNLarissa Niemeyer

Discussion

Member takes

Overview

Multicenter study reveals that negative treatment attitudes and polypharmacy decrease medication adherence in adolescents with psychiatric disorders, highlighting key targets for clinical support.

Key Points

To assess medication attitudes across a diverse psychiatric adolescent population and identify clinical and demographic factors linked to noncomplete adherence.
Conducted a secondary analysis of the multicenter SEMA study comprising N = 75 adolescents aged 12–17 years receiving psychopharmacological therapy.
Assessed treatment attitudes via the Questionnaire on Attitudes Toward Treatment (QATT) and adherence via the Medication Adherence Report Scale (MARS), classifying adherence as complete or noncomplete.
Performed group comparisons alongside multivariable logistic regression to identify independent factors predicting noncomplete medication adherence.
A total of 40% of adolescents were classified as not completely adherent to their medication regimen.
Higher QATT scores, reflecting less favorable medication attitudes, were observed among older adolescents, inpatients, individuals with internalizing disorders, and those with noncomplete adherence.
In multivariable logistic regression, higher QATT scores (OR = 1.05, 95% CI: 1.00–1.10; p = 0.048) and polypharmacy (OR = 3.64, 95% CI: 1.03–12.88; p = 0.046) independently predicted noncomplete medication adherence.

Cite This Study

Handermann et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd4606b95aff0620ec117 https://doi.org/10.1177/10445463261485772

View Full Paper

Ask AI

Bookmark