Key result
Aortic valve replacement was associated with persistent changes in systolic time intervals at 44 hours post-operation, despite normal haemodynamic measurements.
Why the study?
Does aortic valve replacement alter haemodynamics and systolic time intervals early post-operation in patients?
Observational (n=15)
Does aortic valve replacement alter haemodynamics and systolic time intervals early post-operation in patients?
Early after aortic valve replacement, patients exhibit persistent changes in systolic time intervals despite normal hemodynamics, potentially due to myocardial ischemia during cardiopulmonary bypass.
Answers are grounded in this paper and cite their sources.
Normal post-AVR hemodynamics may not reflect full myocardial recovery; leaves open systolic time intervals' prognostic value.
Changes in haemodynamics and in systolic time intervals, early after valve replacement, were studied in a group of 15 patients. Though all the haemodynamic measurements were within normal limits at 44 hours after operation, there was a persistent change in systolic time intervals (shortening of left ventricular ejection time and electromechanical systole, and prolongation of pre-ejection period and increase in the ratio PEP/LVET). The effect of periods of myocardial ischaemia during cardiopulmonary bypass on myocardial function is suggested as the explanation for the changes observed.
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Seabra-Gomes et al. (1976) conducted an observational in Aortic valve replacement (n=15). Aortic valve replacement was evaluated on Changes in haemodynamics and systolic time intervals. Aortic valve replacement was associated with persistent changes in systolic time intervals at 44 hours post-operation, despite normal haemodynamic measurements.
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