Key result
Taussig-Bing anomaly was independently associated with an increased need for percutaneous pulmonary artery interventions (OR 2.8) in patients who underwent an arterial switch operation for transposition of the great arteries.
Why the study?
Pulmonary artery stenosis is common after arterial switch operation for transposition of the great arteries, but differences between balloon angioplasty and stents on right ventricular and pulmonary artery pressures are not well studied.
Are stents more successful than balloon angioplasty at treating pulmonary artery stenosis and improving right ventricular and pulmonary artery pressures in TGA patients after arterial switch operation?
Cohort (n=888)
Yes
Are stents more successful than balloon angioplasty at treating pulmonary artery stenosis and improving right ventricular and pulmonary artery pressures in TGA patients after arterial switch operation?
Answers are grounded in this paper and cite their sources.
Percutaneous pulmonary artery interventions after arterial switch operation are common and generally safe, with stents potentially offering greater success than balloon angioplasty for treating PA stenosis.
Background: Pulmonary artery (PA) stenosis is common after arterial switch operation (ASO) for transposition of the great arteries (TGA). Differences between balloon angioplasty (BA) and stents on right ventricular (RV) and PA pressures are not well studied. Objectives: The purpose of this study was to analyze percutaneous PA interventions' frequency after ASO, complications, and the effects of BA and stents on RV and PA pressures. Methods: All TGA patients with ASO between 1977 and 2022 in 2 Dutch congenital heart centers were included in this multicenter retrospective study. Peri-operative ASO characteristics and pre-intervention and post-intervention invasive and echocardiographic data were analyzed. Seventeen complications, most minor, were reported (13%). Two post-procedural deaths were reported. Conclusions: Percutaneous PA interventions are common after ASO and can be performed safely but caution for serious complications is warranted. Unilateral PA stenosis can impact RV pressures. Stents may be more successful at treating PA stenosis compared to BA.
No takes yet. Share an insight, caveat, or question.
Joosen et al. (2024) conducted a cohort in Transposition of the great arteries (TGA) after arterial switch operation (ASO) (n=888). Taussig-Bing anomaly vs. TGA with intact ventricular septum was evaluated on Presence of percutaneous pulmonary artery interventions (OR 2.8, 95% CI 1.228-6.168, p=0.014). Taussig-Bing anomaly was independently associated with an increased need for percutaneous pulmonary artery interventions (OR 2.8) in patients who underwent an arterial switch operation for transposition of the great arteries.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: