Synthetic Studies Directed toward the Pseurotins. Part I. Synthesis of Related Furan‐3(2H)‐ones

According to a general concept for the total synthesis of pseurotin A (1), a secondary metabolite of Pseudeurotium ovalis STOLK, 5‐[(1S,2S,Z)‐1,2‐dihydroxyhex‐3‐enyl]‐2,2,4‐trimethylfuran‐3(2H)‐one (17) was prepared. It is a model substance for the substituted furan‐3(2H)‐one moiety of 1. The aldol condensation of the aldehyde 26, derived from D‐glucose, and the enolate of ketone 29 served as key reaction.