Key result
Total artificial heart implantation in calves increased circulating blood volume to more than twice the preoperative value after 2 weeks, compared to no change with mitral valve replacement.
Why the study?
Does total artificial heart implantation alter circulating blood volume compared to mitral valve replacement in calves?
Does total artificial heart implantation alter circulating blood volume compared to mitral valve replacement in calves?
In a calf model, total artificial heart implantation leads to a significant increase in circulating blood volume that is not accurately estimated by right atrial pressure.
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Alerts to possible RAP underestimation of volume post-TAH; hypothesis-generating in calves and needs human validation.
Fukamachi et al. (1995) studied Total artificial heart (n=18). Total artificial heart vs. Mitral valve replacement was evaluated on Circulating blood volume (CBV). Total artificial heart implantation in calves increased circulating blood volume to more than twice the preoperative value after 2 weeks, compared to no change with mitral valve replacement.
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