Nitration of N‐(trifluoroacetyl)‐L‐tryptophan methyl ester provides 40% of the anticipated 6‐nitro product and 6–7% of the novel 2‐nitro derivative. The latter compound is deprotected with aqueous acid to form 2‐nitro‐L‐tryptophan. Analogous nitration of L‐tryptophan gives only the 6‐nitro product.
No takes yet. Share an insight, caveat, or question.
Phillips et al. (1988) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: