Isolation and Hypoglycemic Activity of Quinquefolans A,B, and C, Glycans of Panax quinquefolium Roots

This is the authors' abstract. We don't add key points for this paper.

An H2O extract of the American crude drug "Amerika-ninjin" (American ginseng), Panax quinquefolium roots, exhibited significant hypoglycemic activity in mice. Activity-guided fractionation of the extract led to isolation of three glycans, quinquefolans A, B, and C, which displayed hypoglycemic effects in normal and alloxan-induced hyperglycemic mice.