Key result
Older age (P<0.001), diabetes mellitus (P=0.004), and hyperlipidemia (P=0.041) were independently associated with an increased basilar artery pulsatility index in patients with ischemic stroke.
Why the study?
The study was conducted to evaluate the risk factors affecting the basilar artery pulsatility index in ischemic stroke patients.
What are the risk factors affecting the basilar artery pulsatility index on transcranial doppler in ischemic stroke patients?
Observational (n=422)
No
What are the risk factors affecting the basilar artery pulsatility index on transcranial doppler in ischemic stroke patients?
p-value: p=<0.001
Age, diabetes, and hyperlipidemia are significant risk factors affecting the basilar artery pulsatility index in ischemic stroke patients.
May identify risk factors for basilar PI in stroke; leaves open clinical utility pending prospective validation.
Transcranial doppler is a non-invasive method that measures the blood flow velocity and the direction of cerebral blood vessels through the doppler principle. The pulsatility index is an index for measuring the transcranial doppler that reflects the distal vascular resistance and is used as an index for the presence and diffusion of cerebral small vessel diseases. The purpose of this study was to evaluate the risk factors affecting the basilar artery pulsatility index in ischemic stroke patients. From January 2014 to May 2015, 422 patients were selected by measuring the transcranial doppler pulsatility index, considering their basilar artery pulsatility index. Univariate analysis was performed using the basilar artery pulsatility index as a dependent variable. Multiple regression analysis was performed considering the factors affecting the pulsatility index as variables. Univariate analysis revealed age, presence of hypertension, presence of diabetes mellitus, presence of hyperlipidemia, and hematocrit (P0.1) as factors. Multiple regression analysis showed statistically significant results with age (P0.001), presence of diabetes (P=0.004), and presence of hyperlipidemia (P=0.041). The risk factors affecting the basilar artery pulsatility index of transcranial doppler were age, diabetes, and hyperlipidemia. Further research will be needed to increase the cerebral pulsatility index as a surrogate marker of the elderly, diabetes, and hyperlipidemia.
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Jeong et al. (2018) conducted an observational in Ischemic stroke or transient ischemic attack (n=422). Age, diabetes mellitus, and hyperlipidemia vs. Absence of these risk factors / younger age was evaluated on Basilar artery pulsatility index (BA PI) (p=<0.001). Older age (P<0.001), diabetes mellitus (P=0.004), and hyperlipidemia (P=0.041) were independently associated with an increased basilar artery pulsatility index in patients with ischemic stroke.
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