Key result
Patients with end-stage kidney disease receiving hemodialysis experience an annual sudden cardiac death rate of approximately 5%, exceeding the general population risk by 20-fold.
Highlights the exceptionally high risk of sudden cardiac death in hemodialysis patients, which exceeds that of the general population and patients with HFrEF.
It is increasingly recognized that patients with end-stage kidney disease receiving intermittent thrice-weekly hemodialysis are among the highest risk populations for cardiac arrhythmias and sudden cardiac death (SCD). The ∼5% annual SCD rate in patients receiving hemodialysis exceeds the general population risk by 20-fold and even exceeds the rate among patients with heart failure with reduced ejection fraction, the most well-recognized high-risk population.1 Since seminal observations made by Bleyer et al2 more than 30 years ago, multiple studies have confirmed a temporal pattern of cardiac events in patients receiving hemodialysis according to the day of the week and the timing of hemodialysis treatments.
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Patrick H. Pun (2024) conducted an editorial in End-stage kidney disease receiving hemodialysis. Hemodialysis vs. General population was evaluated on Sudden cardiac death. Patients with end-stage kidney disease receiving hemodialysis experience an annual sudden cardiac death rate of approximately 5%, exceeding the general population risk by 20-fold.
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