Key result
Adenosine stress and rest 3D mapping effectively identifies at-risk myocardial tissue in CAD.
Adenosine stress myocardial perfusion SPECT with automated 3D quantitative analysis is a valuable and reliable alternative to exercise stress testing for identifying areas at risk in coronary artery disease, particularly useful when exercise is not feasible.
May support adenosine stress 3D mapping when exercise is infeasible; leaves open prospective validation in CAD.
Coronary Artery Disease (CAD) is one of the most important causes of mortality and morbidity in the world. Nevertheless, Myocardial Perfusion Scintigraphy (MPS) using Single-Photon Emission Computed Tomography (SPECT) with radiopharmaceuticals is still widely used for the non-invasive diagnosis of obstructive CAD and functional imaging of the myocardium at stress.
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Salih et al. (2022) conducted a review in Coronary Artery Disease (n=500). Adenosine stress myocardial perfusion SPECT was evaluated on Quantitation of perfusion deficit areas and comparison to coronary angiographic data. Adenosine stress and rest 3D mapping effectively differentiates myocardial tissue characteristics and identifies areas at risk in patients with coronary artery disease.
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