A simple and efficient method for the synthesis of 2-trifluoromethyl quinolines by means of visible-light-induced radical cyclization of trifluoroacetimidoyl chlorides with alkynes has been developed. This protocol allows the generation of imidoyl radicals by activation of C(sp2)Cl bonds using a photoredox catalyst under mild and environmentally friendly conditions (see scheme).
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Dong et al. (2013) studied this question.
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