Key result
Electrocoagulation of tissues during surgery markedly increases serum CPK activity in the first 7 hours postoperatively to levels seen in intraoperative myocardial infarction.
Why the study?
Does the use of electrocautery increase serum creatine phosphokinase levels in surgical patients?
Does the use of electrocautery increase serum creatine phosphokinase levels in surgical patients?
Electrocautery during surgery can cause marked elevations in serum CPK similar to levels seen in intraoperative myocardial infarction, which could confound the diagnosis of perioperative MI.
Electrocautery may confound perioperative MI diagnosis via CPK elevation; leaves open validation of alternative markers in surgical cohorts.
While serum creatine phosphokinase (CPK) may be slightly elevated following major uncomplicated surgical procedures, the use of electrocoagulation of tissues gives rise during the first 7 hr postoperatively to CPK activity which is as markedly increased as in those patients who sustain intraoperative myocardial infarction.
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Mostert et al. (1970) studied this question. Electrocoagulation of tissues during surgery markedly increases serum CPK activity in the first 7 hours postoperatively to levels seen in intraoperative myocardial infarction.
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