A GC procedure is described for the screening of biological fluids for the presence of basic and neutral drugs. Extracts are chromatographed simultaneously on a two-column system designed so that a wide range of drugs can be detected. A majority of the drugs is readily detectable in blood in concentrations of 0.1 mg per 100 ml. The procedure is illustrated with examples of casework as well as examples of "spiked" blood samples.
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Wells et al. (1975) studied this question.
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