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A single tryptic peptide containing adenylic acid has been isolated from Escherichia coli glutamine synthetase. The amino acid sequence of the peptide is [see PDF for sequence] The radioactivity of the 14C-AMP moiety was released from the peptide during the first Edman degradative cycle, and this was shown to be due to cleavage of the 14C-adenine-ribose bond by trifluoroacetic acid.
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Heinrikson et al. (1970) studied this question.
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