Key result
Apical left ventriculotomy in 5 infants and young children was associated with no early or late deaths and early postoperative ejection fractions >50% in all patients.
Why the study?
Does apical left ventriculotomy preserve left ventricular ejection fraction and avoid significant morbidity in infants and young children requiring cardiac surgery?
Observational (n=5)
Does apical left ventriculotomy preserve left ventricular ejection fraction and avoid significant morbidity in infants and young children requiring cardiac surgery?
Apical left ventriculotomy appears safe and does not significantly impair short-term left ventricular function in infants and young children requiring complex cardiac surgery.
Apical left ventriculotomy may be feasible short-term in select infants; hypothesis-generating and requires prospective validation before wider use.
OBJECTIVES: Incisions in the left ventricle have previously been associated with increased mortality and morbidity, particularly in infants. In order to determine whether this assumption is still true in the current era, we reviewed our recent experience with apical left ventriculotomy in neonates and infants. METHODS: The records of five consecutive patients requiring a left ventriculotomy between 2007 and 2010 were reviewed. Weight and age ranged from 2.6 to 16 kilograms and 5 days to 2 years. The diagnoses were three multiple ventricular septal defects, one rhabdomyoma, and one apical aneurysm. The primary end point was left ventricular ejection fraction, with other end points being intensive care unit length of stay, time to extubation, inotrope requirement, arrhythmias, and mitral valve function. RESULTS: There were no early or late deaths. Although lower than their preoperative values, early postoperative ejection fractions were greater than 50% in all patients. Two patients required no inotropes, and 3 required only minimal support. Hospital length of stay was 9 ± 7 days for multiple ventricular septal defect patients, with intensive care unit stays of 2 to 5 days. There were no postoperative arrhythmias requiring pharmacological therapy, and one patient had a significant reduction in mitral insufficiency postoperatively. CONCLUSIONS: Based on our experience, we believe that an apical left ventriculotomy does not significantly impair left ventricular function even in small infants, and is not associated with significant morbidity, based on short-term follow-up. Although the long-term effects are still unknown, early results suggest that a left ventriculotomy may safely be used when alternative approaches are inadequate for complex cardiac defects.
No takes yet. Share an insight, caveat, or question.
Goldberg et al. (2012) conducted an observational in Complex cardiac defects requiring left ventriculotomy (n=5). Apical left ventriculotomy was evaluated on left ventricular ejection fraction. Apical left ventriculotomy in 5 infants and young children was associated with no early or late deaths and early postoperative ejection fractions >50% in all patients.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: