We propose and demonstrate a novel fiber bundle imaging based on spatial compounding induced by random transverse motion to remove the pixelation effect, to improve resolution, and to increase image quality. The experimental results using a USAF target and pyramidal neuron cell showed that 20-frame compounding improved image quality (contrast-to-noise ratio by >9 dB, global SNR by >6 dB, equivalent number of looks by >1.8 times, and 1/β by >1.5 times), resolution by better than 2 μm, and completely eliminated pixelation artifact.
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Cheon et al. (2014) studied this question.
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