Case 31-1987

Presentation of CaseA 50-year-old woman was admitted to the hospital because of a seizure, fever, and acidosis.There was a history of hypertension, with the more recent development of end-stage renal disease that was believed to be nephrosclerosis. Two months before entry a cadaveric renal transplantation was performed; the postoperative course was uncomplicated. Immunosuppression consisted of cyclosporine, 700 mg daily, and adrenocorticoid therapy that began with methylprednisolone, 200 mg on the day of operation, and was tapered to prednisone, 20 mg daily, by the fifth postoperative day. She was discharged on cyclosporine, 350 mg twice daily, and prednisone, 20 . . .